Dr. Larry Fisher is on a quest to learn who and why some type 2 patients experience affective and anxiety disorders, depressive affect and diabetes-related distress over time – and some do not.
UCSF researchers are often honored by the diabetes community for their significant scientific achievements. It is equally meaningful when our clinicians receive well-deserved recognition for the passionate care they provide to families, and for their cutting-edge clinical research efforts.
Researchers at the Barbara Davis Center in Denver have identified a fourth autoantibody to help predict type 1 diabetes, ZnT8. This autoantibody, in combination with the others that had been previously identified, has raised our ability to detect “pre-diabetes” to 98 percent.
In December, the Institute for Regeneration Medicine at UCSF was renamed the Eli and Edythe Broad Center of Regeneration Medicine at a press conference attended by Governor Arnold Schwarzenegger, Chair of the California Institute for Regenerative Medicine (and Diabetes Center Leadership Council Member) Robert Klein, generous philanthropists Eli and Edythe Broad, and university leaders.
UCSF Pediatric Diabetes Program Director Steve Gitelman, MD has partnered with the Immune Tolerance Network (ITN) to launch a study involving ATG , or anti-thymocyte globulin, to see if this drug can halt the progression of new onset type 1 diabetes. The START trial (Study of Thymoglobulin to Arrest Type 1 Diabetes) hopes to recruit 66 volunteers, 18 – 35 years of age, within six weeks of diagnosis.
On November 20, UCSF held a panel discussion on stem cell research that was moderated by KQED Radio’s Michael Krasny, PhD. Diabetes Center researcher Matthias Hebrok, PhD joined an esteemed group of stem cell researchers to discuss the potential of stem cells to cure disease. [ Forum, KQED ]
Two common cancer drugs have been shown to both prevent and reverse type 1 diabetes in a mouse model of the disease, according to research conducted at the University of California, San Francisco. The drugs – imatinib (marketed as Gleevec) and sunitinib (marketed as Sutent) – were found to put type 1 diabetes into remission in 80 percent of the test mice and work permanently in 80 percent of those that go into remission.
In recent breakthroughs, researchers have developed a process for reprogramming fully grown adult cells back into something akin to embryonic stem cells, called induced pluripotent stem cells, or iPS cells.
On Friday, November 13, a California Superior Court Judge ruled against a provision of an agreement between the American Diabetes Association (ADA) and the California Department of Education that would ensure students are provided appropriate care in the classroom.
The immune system is a powerful defensive weapon the body uses to identify and destroy invading organisms like bacteria and viruses. The cells of the immune system constantly patrol the body looking for such invaders. However, this defensive system must be carefully educated to distinguish between foreign material and the body’s own tissues, in order to prevent the immune system from mistakenly attacking its own body.
A new educational resource for diabetes is now available on the Internet, thanks to the UCSF Diabetes Teaching Center (DTC). Since it was launched in July 2008, thousands of families have visited the site. DTC Medical Director Martha Nolte Kennedy, MD and her staff are pleased that this website is providing diabetes education and self-management skills to the growing numbers worldwide who have limited access to diabetes specialists.
Last month, Doug Hanahan, PhD was elected to the prestigious Institute of Medicine (IOM), an organization that serves as adviser to the nation to improve health. Established in 1970 under the charter of the National Academy of Sciences, the IOM provides independent, objective, evidence-based advice to policymakers, health professionals, the private sector, and the public. Dr. Hanahan is a member of both the UCSF Diabetes Center and the Helen Diller Family Comprehensive Cancer Center.
Jeff Bluestone PhD, Mike German MD, and Matthias Hebrok PhD were recently awarded a three year JDRF Network Grant to explore Human Embryonic Stem Cell Source for Beta Cell Replacement.