People with Type 1 Diabetes for five or more years who are 8 years or older
Study Name: Evaluation of residual beta cell function and immunologic features in patients with longstanding type 1 diabetes.
Study Sponsors: National Institute of Health
Principal Investigator: Stephen E. Gitelman, M.D., Director of the Pediatric Diabetes Program at U.C.S.F.
Who can sign up for this study? Volunteers 8 years or older who have had type 1 diabetes for five or more years and have a hemoglobin A1c < 9.5%.
In addition, volunteers may not:
- Be pregnant
- Prior or current use of immune altering drugs such as steroids
- Have another long term chronic illness
What is this study about? This study aims to evaluate differences in the immune systems of people who have had type 1 diabetes for five or more years who still make some insulin versus those who do not. It will also establish a blood bank for future studies of type 1 diabetics.
What will happen in this study? All volunteers will undergo a screening visit where they will be asked questions about their medical history and will undergo a blood draw. If that blood draw determines that they are still making some insulin, they will be asked to return for a 4 hour mixed meal tolerance test. Volunteers may agree to be contacted for future research.
How long will this study last? Volunteers will be followed for these 2 visits only unless they agree to be contacted for future research.
Reimbursement: All volunteers will be reimbursed $25 for the initial blood draw, and $100 for the mixed meal tolerance test. Parking during the study visits will also be reimbursed.