Publications

Our faculty members publish numerous articles in scientific journals.  These articles appear below and may also be accessed on the webpage of each faculty member.

Ogasawara, K., Hamerman, J.A., Hsin, H., Chikuma, S., Jordan, H., Chen, T., Pertel, T., Carnaud, C., Bluestone, J.A., and Lanier, L.L. (co-senior authors). Impairment of NK cell function by NKG2D modulation in NOD mice. Immunity. 18:41-51, 2003.
Jeff Bluestone, PhD
Ogasawara, K., Hamerman, J.A., Ehrlich, L.R., Bour-Jordan , H., Bluestone, J.A., and Lanier, L.L. NKG2D blockade prevents autoimmune diabetes in NOD mice. Immunity, 20: 757-767, 2004.
Jeff Bluestone, PhD
Eagar, T.N., Turley, D.M., Padilla, J., Karandikar , N.J. , Tan, L.J., Bluestone, J.A., and Miller, S.D. CTLA-4 regulates expansion and differentiation of Th1 cells following induction of peripheral T cell tolerance. Eur. J. Immunol., J. Immunol. , 172: 7442-7450, 2004.
Jeff Bluestone, PhD
Tang, Q., Henriksen, K.J., Bi, M., Finger, E.B., Szot, G., Ye, J., Masteller, E., McDevitt, H., Bonyhadi, M, and Bluestone, J.A. In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes. J. Exp. Med., 199:1455-1465, 2004.
Jeff Bluestone, PhD
Eagar, T.N., Tang, Q., Wolfe, M., He, Y., Pear, W.S., and Bluestone, J.A. Notch 1 signaling regulates peripheral T cell activation. Immunity 20:407-15. 2004.
Jeff Bluestone, PhD
Bour-Jordan, H., Salomon, B., Thompson, H., Szot, G.L., Bernhard, M., Bluestone, J.A. Costimulation controls the development of diabetes in NOD mice by altering the balance of pathogenic and regulatory T cells. J. Clin. Invest. 114:979¡V987, 2004.
Jeff Bluestone, PhD
Tang Q., Boden E. K., Henriksen, K.J., Bour-Jordon, H., Bi, M., and Bluestone, J.A. Distinct roles of CTLA-4 and TGF-beta in CD4+CD25+ regulatory T cell function. Eur. J. Imm. 34: 2996-3005, 2004.
Jeff Bluestone, PhD
Herold, K.C., Gitelman, S.E., Masharani, U., Hagopian, W., Bisikirska, B., Donaldson, D., Rother, K., Diamond, B., Harlan, D.M., Bluestone, J.A. A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes. Diabetes 54:1763-9, 2005.
Jeff Bluestone, PhD
Masteller, E. L., Warner, M.R., Tang, Q., Tarbell, K.V. McDevitt, H., and Bluestone J.A. Expansion of functional endogenous antigen-specific CD4+CD25+ regulatory T cells from nonobese diabetic mice. J. Immunol. 175:3053-9, 2005.
Jeff Bluestone, PhD
Chikuma, S., Abbas, A. and Bluestone, J. B7-independent inhibition of T cells by CTLA-4. J. Immunol. 175: 177 ¡V 181, 2005.
Jeff Bluestone, PhD
Youngren J, Gable K, Peñaranda C, Maddux B, Zavodovskaya M, Lobo M, Campbell M, Goldfine ID. Nordihydroguaiaretic acid (NDGA) inhibits the IGF-1 and c-erbB2/HER2/neu receptors and suppresses growth in breast cancer cells. Breast Cancer Research Treatment. 94 (1):37-46, 2005.
Ira Goldfine, M.D.
Maddux B, Chang Y-N, Accili D, McGuinness OP, Youngren JF, Goldfine ID. Overexpression of the insulin receptor inhibitor PC-1/ENPP1 induces insulin resistance and hyperglycemia. Am J Physiol Endocrinol Metab. In Press, 2006.
Ira Goldfine, M.D.
Stephen Rosenthal, M.D.
Stephen Rosenthal, M.D.
Stephen Rosenthal, M.D.
Stephen Rosenthal, M.D.
Adi S, Cheng Z-Q, Zhang P-L, Wu NY, Mellon SH, Rosenthal SM: Opposing early inhibitory and late stimulatory effects of insulin-like growth factor-I on myogenin gene transcription. J Cell Biochem 78:617-626, 2000.
Stephen Rosenthal, M.D.
Stephen Rosenthal, M.D.
Cheng Z-Q, Adi S, Hsiao D, Woo EJ, Filvaroff EH, Gustafson TA, Rosenthal SM: Functional inactivation of the IGF-I receptor delays differentiation of skeletal muscle cells. J Endocrinol 167:175 - 182, 2000.
Stephen Rosenthal, M.D.
Stephen Rosenthal, M.D.
Hernandez-Sanchez C, Werner H, Roberts Jr C, Woo EJ, Hum D, Rosenthal SM, LeRoith D: Differential regulation of insulin-like growth factor-I (IGF-I) receptor gene expression by IGF-I and basic fibroblastic growth factor. J Biol Chem 272:4663-4670, 1997.
Stephen Rosenthal, M.D.
Stephen Rosenthal, M.D.
Stephen Rosenthal, M.D.
Stephen Rosenthal, M.D.
Clément K*, Vaisse C*, Lahlou N, Cabrol S, Pelloux V, Cassuto D, Gourmelen M, Dina C, Chambaz J, Lacorte J-M, Basdevant A, Bougnères P, Lebouc Y, Froguel P & Guy-Grand B.(1998): A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction. Nature 392:398-400.
Christian Vaisse, M.D., Ph.D
Vaisse C., Clément K., Durand E., Legall A., Bonhomme G., Basdevant A., Guy-Grand B., Froguel P. (2000) Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity. Journal of Clinical Investigation 106:253-262.
Christian Vaisse, M.D., Ph.D
 
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