Chikuma, S., Abbas, A. and Bluestone, J. A. B7 independent inhibition of T cells by CTLA-4. J. Immunol. 175: 177 ¡V 181, 2005.

Masteller, E. L., Warner, M.R., Tang, Q., Tarbell, K.V. McDevitt, H., and Bluestone J.A. Expansion of functional endogenous antigen-specific CD4+CD25+ regulatory T cells from NOD mice. J. Immunol. 175:3053-9, 2005.

Herold, K.C., Gitelman, S.E., Masharani, U., Hagopian, W., Bisikirska, B., Donaldson, D., Rother, K., Diamond, B., Harlan, D.M., Bluestone, J.A. A single course of anti-CD3 monoclonal antibody hOKT3ƒ×1(Ala-Ala) results in improvement in c-peptide responses and clinical parameters for at least 2 years after onset of Type 1 Diabetes. Diabetes 54:1763-9, 2005.

Tang Q., Boden E. K., Henriksen, K.J., Bour-Jordon, H., Bi, M., and Bluestone, J.A. Distinct roles of CTLA-4 and TGF-ƒÒ in CD4+CD25+ regulatory T cell function Eur. J. Imm. 34: 2996-3005, 2004.

Bour-Jordan, H., Salomon, B., Thompson, H., Szot, G.L., Bernhard, M., Bluestone, J.A. Costimulation controls the development of diabetes in NOD mice by altering the balance of pathogenic and regulatory T cells. J. Clin. Invest. 114:979¡V987, 2004.

Eagar, T.N., Tang, Q., Wolfe, M., He, Y., Pear, W.S., and Bluestone, J.A. Notch 1 Signaling Regulates Peripheral T Cell Activation, Immunity 20:407-15. 2004.

Tang, Q., Henriksen, K.J., Bi, M., Finger, E.B., Szot, G., Ye, J., Masteller, E., McDevitt, H., Bonyhadi, M, and Bluestone, J.A. In vitro expanded antigen-specific regulatory T cells suppress autoimmune diabetes. J. Exp. Med., 199:1455-1465, 2004.

Eagar, T.N., Turley, D.M., Padilla, J., Karandikar , N.J. , Tan, L.J., Bluestone, J.A., and Miller, S.D. CTLA-4 regulates expansion of differentiation of Th1 cells following induction of peripheral T-cell tolerance. Eur. J. Immunol., J. Immunol. , 172: 7442-7450, 2004.

Ogasawara, K., Hamerman, J.A., Ehrlich, L.R., Bour-Jordan , H., Bluestone, J.A., and Lanier, L.L. NKG2D blockade prevents autoimmune diabetes in NOD mice, Immunity, 20: 757-767, 2004.

Eagar, T.N., Tang, Q., Wolfe, M., He, Y., Pear, W.S., and Bluestone, J.A. Notch 1 Signaling Regulates Peripheral T Cell Activation, Immunity 20:407-15. 2004. Ogasawara, K., Hamerman, J.A., Hsin, H., Chikuma, S., Jordan, H., Chen, T., Pertel, T., Carnaud, C., Bluestone, J.A., and Lanier, L.L. (co-senior authors). Impairment of NK cell function by NKG2D modulation in NOD mice, Immunity. 18:41-51, 2003.

Bour-Jordan, H., Grogan, J.L. Tang Q., Auger , J.A., Locksley, R.M., and Bluestone, J.A. CTLA-4 regulates the requirement for cytokine-induced signals in T(H)2 lineage commitment, Nature Immunol. 4:182-188, 2003. Tang, Q., Henriksen, K.J., Boden, E.K., Tooley, A.J., Subudhi, S.K., Zheng X.X., Strom, T.B., Bluestone J.A. Cutting Edge: CD28 controls peripheral homeostasis of CD4 + CD25 + regulatory T cells. J. Immunol 171:3348-52, 2003.

Belghith, M., Bluestone, J.A., Barriot, S., Garcia, C., Bach, J-F., Chatenoud, L. TGF- b dependent mechanisms mediate restoration of self-tolerance induced by anti-CD3 antibodies in overt autoimmune diabetes. Nature Medicine 9:1202-8, 2003.

Chikuma, S., Imboden, J. B. and Bluestone, J.A. Negative regulation of T cell receptor-lipid raft interaction by cytotoxic T lymphocyte associated antigen-4, J. Exp. Med. 197:129-135 2003.

...